“There are also collagen-enhancing therapies that help improve skin firmness. It is very important to discuss this concern with your healthcare provider during the initial consultation of GLP-1 therapy because preventive strategies are an effective way to avoid these complications,â€� Jonathan Jennings, MD, board certified internist with Medical 91ÌÒÉ«, told Healthline. Would you like to book an appointment with Dr. Jonathan Jennings?